The start of the new Serie A season is still a month away, and Roma have a game in hand.
With two games to go, the Giallorossi are now 10 points clear of their rivals in the race for the top four.
However, the game in Rome is likely to be decided by a score of 1-0.
In their previous meeting, the Roma defence gave Lazio the lead in the last minute, but the Giarettin outfit held on.
They have a goal to spare and a win to win in Rome could see them secure a Champions League spot.
With five points from five games, Roma have the chance to move into the Europa League places, while Lazio will need to defend their title with a win.
Here is what you need to know ahead of the match.
How will this game unfold?
After their 3-1 win over Bologna on Wednesday, Roma head into the match with the same level of confidence as they did on Wednesday.
“We want to get back to our basics,” Roma coach Francesco Guidolin said.
“They are strong, they are strong.
We are not the same team as we were on Tuesday.
We need to get the result and be consistent.”
With four wins from five Serie A matches this season, Lazio remain unbeaten in their last six matches.
They beat Udinese 1-1 at home on Wednesday but the Italians are now six points behind Roma on goal difference.
Roma, however, have lost only once in their previous six matches and have also drawn four times.
They are currently fourth in the table.
What are the teams playing?
Roma: The Rossoneri have been without midfielder Giorgio Chiellini for the majority of the season, having replaced him with Leonardo Bonucci.
The Italian has scored four goals and assisted two others this season.
They will be without striker Alessandro Florenzi and defender Luca Gasparotto, who are both sidelined by injuries.
“There is a lot of speculation about Florenzo’s future,” Gialloro said.
In his absence, Chielli has been one of the main sources of creativity for the Gialls.
With the number of passes being limited, Chies is one of Roma’s main options to score.
Lazio’s defence is one to watch.
They’ve been without defender Paulo Dybala for a month due to a knee injury.
Their only other defender is goalkeeper Gianluigi Donnarumma.
“I don’t think Lazio have played well for long,” GiALLORO said.
Lazioles starting XI: Andrea Dossena, Roberto Bacca, Giampaolo Pazzini, Federico Vitic, Alessandro Nesta, Giorgi Nesta (GK), Giorgos Karagounis, Alessio Romagnoli, Domenico Marrone (G), Domenic Di Giorgetto (D), Davide Vigano, Stefano Bono (Gk), Stefano Mazzarri (D) Lazios starting XI for Roma v Lazio (4-4-2): Giorgilio Chiello, Angelo Matri, Mario Gasparotti, Alessandra Mazzone, Giampiero D’Ambrosio, Stefania Gazzi, Marco Mancini, Simone Brancati, Giacomo Di Marzo, Simone Stortoni, Stefan Bosini, Stefane Mancinelli (D).
Giacomo Di Mauro is set to start in the right back role and Giorgianni Lilliardini will be the main defensive midfielder.